There is important information you need to know about ELMIRON® (pentosan polysulfate sodium) when you are reading about it on this site. This includes the use the FDA has approved for ELMIRON®, information on risks, and instructions about how to safely use ELMIRON®.

For more information, please see the ELMIRON® Product Information and discuss any questions you may have with your doctor.


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    benign prostatic hypertrophy (BPH):
    A noncancerous growth of the prostate gland that is common in men over age 50.
    A muscular, sac-like organ, located in the pelvic area, that stores urine.
    chronic pelvic pain (CPP):
    Pain in the pelvic area that lasts 6 months or more.
    Examination of the urinary bladder by means of an instrument (cystoscope) inserted into it through the urethra.
    ELMIRON®* (pentosan polysulfate sodium):
    The only oral medication approved by the FDA for treating the relief of bladder pain or discomfort associated with IC. View Important Safety Information
    A condition in which endometrial tissue is found outside of its normal location (lining inside the uterus), and instead found in sites like the uterine walls, fallopian tubes, the ovaries, and other sites within or, rarely, outside the pelvis – causing pelvic pain.
    Acute or chronic inflammation/infection of the epididymis – a long, tightly-coiled tube that lies behind each testicle, which collects and helps transport sperm made by the testicles prior to ejaculation.
    glycosaminoglycans (GAG):
    A long protein and carbohydrate substance, which forms the layer lining the inside of the bladder. The GAG layer acts as a barrier to keep urine from irritating the bladder wall.
    Drug used as an anticoagulant – a substance that inhibits the blood from clotting.
    interstitial cystitis (IC):
    A chronic condition of the bladder characterized by urinary urgency, frequency, and pelvic pain in the absence of bacterial infection or other definable pathologies.
    intravesical instillation:
    Administration of a treatment into the bladder.
    nonbacterial prostatitis (NBP):
    Inflammation of the prostate gland, also known as chronic pelvic pain in men.
    overactive bladder (OAB):
    Condition in which the bladder muscles contract excessively. For many people, this activity may appear as symptoms like wetting incidents, strong and sudden urges to urinate, and/or urinating more than 8 times per 24 hours (including 1 or more times during the night).
    Inflammation of the prostate gland. Symptoms include pain in the perineal area, frequency or retention of urine, and, if severe, fever and chills.
    Associated with the area between the anus and the posterior part of the external genitalia.
    One of 2 thick-walled tubes, about 12 inches long, that transports urine from the kidney to the urinary bladder.
    Small tubular structure that drains urine from the bladder, passing it to the outside. In women it is very short, located behind the pubis between the clitoris and the vaginal opening; in men it is much longer, passing from the bladder through the prostate gland into the penis, and serves as the passageway for semen during ejaculation.
    urethral syndrome:
    Lower abdominal aching and cramping, urinary frequency and other symptoms – without evidence of urinary infection; such as painful or difficult urination, urinary straining, and low back pain.
    The sudden, compelling urge to urinate.
    urinary tract infection (UTI):
    Any infection of any of the organs of the urinary system; more common in women than in men, and most often caused by bacteria. Symptoms include frequency, burning pain during urination, and sometimes blood in the urine.
    Chronic discomfort of the external genitalia of the female, with complaints of burning and superficial irritation.