There is important information you need to know about ELMIRON® (pentosan polysulfate sodium) when you are reading about it on this site. This includes the use the FDA has approved for ELMIRON®, information on risks, and instructions about how to safely use ELMIRON®.

For more information, please see the ELMIRON® Product Information and discuss any questions you may have with your doctor.

A better understanding of interstitial cystitis can lead to better treatment.

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    If you do, in fact, have interstitial cystitis (IC) or think you might have IC, it's important to know that it's a treatable medical condition. Your doctor can help you manage your symptoms and find the IC treatment that's right for you. Although there is no known cure for IC, there may be other treatment options that may bring relief—some more invasive than others. Talk to your doctor about the treatment options best for you.

    Lifestyle and Diet Changes

    In addition to traditionally prescribed treatments for IC, some IC patients may find that they experience some degree of temporary symptom relief by making certain IC diet and lifestyle changes. Learn more about managing and living with IC.

    Oral Therapy

    Oral therapy is medication that you take by mouth.

    ELMIRON® (pentosan polysulfate sodium) is the only oral medication that's FDA approved to treat the bladder pain or discomfort associated with IC. It's available by prescription only, and is a capsule you take 3 times a day.

    It's important to continue your treatment as directed by your doctor. And since symptom improvement is gradual, it's important to keep taking ELMIRON® as prescribed by your doctor. If you have not experienced symptom improvement by 6 months of therapy, you should talk to your doctor.


    • ELMIRON® should not be taken if you have a known hypersensitivity to the drug or similar drugs.
    • ELMIRON® is a weak blood thinner (anticoagulant) which may increase bleeding. Call your doctor if you will be undergoing surgery or if you are taking or will begin taking anticoagulant therapy such as warfarin sodium, heparin, high doses of aspirin, or anti-inflammatory drugs such as ibuprofen.
    • The most common side effects are hair loss, diarrhea, nausea, blood in the stool, headache, rash, upset stomach, abnormal liver function tests, dizziness, and bruising.

    Learn more about using ELMIRON®.


    Intravesical Therapies

    With intravesical therapy, medication is instilled directly into the bladder for relief.

    In intravesical therapy for IC, the bladder is filled with a solution that is held for varying periods of time, before it is emptied. This procedure is usually conducted in your doctor's office or a hospital setting, and usually with local anesthesia.

    What Not to Do

    Because the symptoms of IC are like those of bladder infections, helpful friends may suggest the same treatments that they used for a bacterial urinary tract infection (UTI). Be careful — simple home remedies (such as cranberry juice or various herbs) used for UTIs may actually make your IC condition worse. Your best bet is to seek medical advice from your doctor.

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